TLR9 -> TLR9_TLR9
Viral_Bacterial_CpG -> TLR9_TLR9
External_Activator -> NOS2Agene
IRF2 -|? NOS2Agene
External_Activator -> IFNGR1
External_Activator -> LMNA
External_Activator -> MAP3K7IP1
TNF_IKBKG_Complex -> NFKBIA_RELAp65_NFKB1p50
RELA_p65 -> NFKBIA_RELAp65_NFKB1p50
IKBKG_CHUK_IKBKB -> NFKBIA_RELAp65_NFKB1p50
NFKBIA -> NFKBIA_RELAp65_NFKB1p50
NFKB1_p50 -> NFKBIA_RELAp65_NFKB1p50
CASP6cytoplasm -> CASP6nucleus
ProCASP2 -> CASP2
Fragmented_DNAcytoplasm -> CASP2
IRF3_IRF3cytoplasm -> IRF3_IRF3nucleus
External_Activator -> NFKB2p100
TICAM1 -> TLR3_TICAM1_TICAM2
TLR3_TLR3 -> TLR3_TICAM1_TICAM2
TICAM2 -> TLR3_TICAM1_TICAM2
STAT1 -> STAT1_STAT2
STAT2 -> STAT1_STAT2
Diacyl_Lipopeptides -> TLR2_TLR6
TLR6 -> TLR2_TLR6
TLR2 -> TLR2_TLR6
TLR3_TICAM1_TICAM2 -> TLR3_TICAM1_TICAM2_TBK1
TBK1 -> TLR3_TICAM1_TICAM2_TBK1
TNFRSF10A -> TNFSF10_TNFRSF10A
TNFSF10 -> TNFSF10_TNFRSF10A
External_Activator -> TBK1
IRF7_IRF7cytoplasm -> IRF7_IRF7nucleus
CD40 -> CD40_CD40LG
CD40LG -> CD40_CD40LG
Virus -> dsRNA
IFNA -> IFNA_IFNA
PRKCD -> STAT1_STAT1cytoplasm
STAT1 -> STAT1_STAT1cytoplasm
External_Activator -> IFNAR1
External_Activator -> DAXX
IRF1_IRF1nucleus -> TAP1gene
IRF2 -> TAP1gene
External_Activator -> APAF1
External_Activator -> TOLLIP
TP53nucleus -> IFR5gene
STAT1_STAT1_IRF9nucleus -> IFR5gene
External_Activator -> CREBBP
Mitochondrial_Activator -> BAD
BAG4_TNFRSF1A -> TNF_BAG4_TNFRSF1A
TNF -> TNF_BAG4_TNFRSF1A
TLR3_TICAM1_TICAM2_TRAF6 -> MAP3K7IP1_MAP3K7IP2_MAP3K7
MAP3K7 -> MAP3K7IP1_MAP3K7IP2_MAP3K7
TLR9_MYD88_IRAK1_IRAK4_TRAF6 -> MAP3K7IP1_MAP3K7IP2_MAP3K7
TLR7_MYD88_IRAK1_IRAK4_TRAF6 -> MAP3K7IP1_MAP3K7IP2_MAP3K7
MAP3K7IP2 -> MAP3K7IP1_MAP3K7IP2_MAP3K7
MAP3K7IP1 -> MAP3K7IP1_MAP3K7IP2_MAP3K7
TLR2_TLR6_TOLLIP_MYD88_IRAK1_IRAK4_TRAF6 -> MAP3K7IP1_MAP3K7IP2_MAP3K7
TLR5_MYD88_IRAK1_IRAK4_TRAF6 -> MAP3K7IP1_MAP3K7IP2_MAP3K7
TLR1_TLR2_TIRAP_MYD88_IRAK2_IRAK1_IRAK4_TRAF6 -> MAP3K7IP1_MAP3K7IP2_MAP3K7
ILIB_IL1R1_MYD88_IRAK1_IRAK4_TRAF6 -> MAP3K7IP1_MAP3K7IP2_MAP3K7
External_Activator -> IKBKB
External_Activator -> TRAF2cytoplasm
External_Activator -> FAF1
TLR7 -> TLR7_TLR7
ssRNA -> TLR7_TLR7
TNF_BAG4_TNFRSF1A -> TNF_TNFRSF1A
External_Activator -> TICAM1
IRF5_IRF5cytoplasm -> IRF5_IRF5nucleus
TRAF6 -> TLR7_MYD88_IRAK1_IRAK4_TRAF6
TLR7_MYD88_IRAK1_IRAK4 -> TLR7_MYD88_IRAK1_IRAK4_TRAF6
CHUK -> CHUK_CHUK
MAP3K14 -> CHUK_CHUK
External_Activator -> CFLAR
TRAF2cytoplasm -> TNF_TNFRSF1A_FADD_TRADD_TRAF2_RIPK1
RIPK1 -> TNF_TNFRSF1A_FADD_TRADD_TRAF2_RIPK1
TNF_TNFRSF1A_FADD_TRADD -> TNF_TNFRSF1A_FADD_TRADD_TRAF2_RIPK1
TLR4_TICAM1_TICAM2 -> IKBKE_TBK1
IKBKE -> IKBKE_TBK1
TBK1 -> IKBKE_TBK1
FASLG_FAS_FADD_FAF1_DAXX -> CASP8
ProCASP8 -> CASP8
TNFSF10_TNFSF10B_FADD -> CASP8
TNFSF10_TNFRSF10A_FADD -> CASP8
FASLG_FAS_FADD_FAF1_DAXX_CFLAR -> CASP8
IFNB1 -> IFNB1_IFNB1
FADD -> TNFSF10_TNFRSF10A_FADD
TNFSF10_TNFRSF10A -> TNFSF10_TNFRSF10A_FADD
CASP3cytoplasm -> CASP3gene
IRF5_IRF5nucleus -> CASP3gene
IRF1_IRF1_Activator -> PKC
RELAp65_NFBK1p50nucleus -> BCL2A1gene
TLR1_TLR2_TIRAP_MYD88_IRAK2_IRAK1_IRAK4 -> TLR1_TLR2_TIRAP_MYD88_IRAK2_IRAK1_IRAK4_TRAF6
TRAF6 -> TLR1_TLR2_TIRAP_MYD88_IRAK2_IRAK1_IRAK4_TRAF6
External_Activator -> TRAF5
FASLG_FAS_FADD_FAF1_DAXX -> FASLG_FAS_FADD_FAF1_DAXX_CFLAR
CFLAR -> FASLG_FAS_FADD_FAF1_DAXX_CFLAR
IRF3_IRF7cytoplasm -> IRF3_IRF7nucleus
External_Activator -> SOCS3
External_Activator -> JAK2
BAG4 -> BAG4_TNFRSF1A
TNFRSF1A -> BAG4_TNFRSF1A
CASP6_Activator -> ProCASP6
External_Activator -> ProCASP8
IRF8 -> IL1Bgene
SPI1 -> IL1Bgene
RELAp65_NFBK1p50nucleus -> SOD2gene
IKBKE_TBK1 -> IRF7
IRF5_IRF5nucleus -> IFIT1gene
IRF1_IRF1cytoplasm -> IRF1_IRF1nucleus
TLR5 -> TLR5_TLR5
Flagellin -> TLR5_TLR5
IFNAR -> STAT2
External_Activator -> IRAK4
Mitochondrial_Activator -> BAK1
STAT1_STAT1nucleus_p2 -> IRF1gene
External_Activator -> JAK1
External_Activator -> PARP
ENDOGcytoplasm -> ENDOGnucleus
RELAp65_NFBK1p50nucleus -> CFLARgene
IRF2_Activator -> IRF2
External_Activator -> ProCASP1
External_Activator -> TRAF6
External_Activator -> IRF9
IFNGR1 -> IFNGR
IFNG -> IFNGR
JAK2 -> IFNGR
IFNGR2 -> IFNGR
SOCS3 -|? IFNGR
SOCS1 -|? IFNGR
PTPN2 -|? IFNGR
External_Activator -> TRADD
External_Activator -> DNA
IRF1_IRF1nucleus -> IL15gene
Apoptosome -> CASP3cytoplasm
ProCASP3 -> CASP3cytoplasm
CASP4 -> CASP3cytoplasm
BIRC4cytoplasm -|? CASP3cytoplasm
CASP8 -> CASP3cytoplasm
BIRC2 -|? CASP3cytoplasm
NFKB2p52_RELBcytoplasm -> NFKB2p52_RELBnucleus
IPARP -> Inactive_DNA_Repair
RELAp65_NFBK1p50nucleus -> IER3gene
TLR9_MYD88_IRAK1_IRAK4_TRAF6 -> TLR9_MYD88_TRAF6
EIF2S1 -> Inactivation_of_Protein_Synthesis
External_Activator -> FADD
External_Activator -> BIRC2
IRF1_IRF1nucleus -> IL12Bgene
RELAp65_NFBK1p50nucleus -> BCL2L1gene
External_Activator -> MAP3K7IP2
RELAp65_NFBK1p50nucleus -> BCL2A1
IRAK2 -> TLR1_TLR2_TIRAP_MYD88_IRAK2_IRAK1_IRAK4
IRAK4 -> TLR1_TLR2_TIRAP_MYD88_IRAK2_IRAK1_IRAK4
TLR1_TLR2 -> TLR1_TLR2_TIRAP_MYD88_IRAK2_IRAK1_IRAK4
IRAK1 -> TLR1_TLR2_TIRAP_MYD88_IRAK2_IRAK1_IRAK4
MYD88 -> TLR1_TLR2_TIRAP_MYD88_IRAK2_IRAK1_IRAK4
TIRAP -> TLR1_TLR2_TIRAP_MYD88_IRAK2_IRAK1_IRAK4
cGAS2 -> Cell_Shrinkage
cLMNA -> Cell_Shrinkage
External_Activator -> TLR5
GAS2 -> cGAS2
CASP3nucleus -> cGAS2
CHUK -> IKBKG_CHUK_IKBKB
IKBKB -> IKBKG_CHUK_IKBKB
TLR3_TICAM1_TICAM2_RIPK1_RIPK3 -> IKBKG_CHUK_IKBKB
MAP3K7IP1_MAP3K7IP2_MAP3K7 -> IKBKG_CHUK_IKBKB
IKBKG -> IKBKG_CHUK_IKBKB
External_Activator -> IFNGR2
External_Activator -> PTP
External_Activator -> FAS
TP53nucleus -> APAF1gene
TNFRSF1B -> TNF_TNFRSF1B
TNF -> TNF_TNFRSF1B
TLR7_TLR7 -> TLR7_MYD88_IRAK1_IRAK4
IRAK4 -> TLR7_MYD88_IRAK1_IRAK4
IRAK1 -> TLR7_MYD88_IRAK1_IRAK4
MYD88 -> TLR7_MYD88_IRAK1_IRAK4
Proteasome -> NFKB2p52_RELBcytoplasm
NFKB2p100_RELB_Ub -> NFKB2p52_RELBcytoplasm
Bacteria -> Triacyl_Lipopeptides
External_Activator -> ProCASP4
TNFSF13B_TNFRSF17_TRAF5 -> MAP3K14
CD40_CD40LG_TRAF3 -> MAP3K14
TNF_TNFRSF1B_TRAF2 -> MAP3K14
BCL2L1mitochondria -> BCL2L1_BAD
BAD -> BCL2L1_BAD
FADD -> TNFSF10_TNFSF10B_FADD
TNFSF10_TNFSF10B -> TNFSF10_TNFSF10B_FADD
TP53nucleus -> BBC3gene
RELAp65_NFKB1p50cytoplasm -> RELAp65_NFBK1p50nucleus
TNFSF13B_TNFRSF17 -> TNFSF13B_TNFRSF17_TRAF5
TRAF5 -> TNFSF13B_TNFRSF17_TRAF5
Virus -> ssRNA
External_Activator -> ATF2
Ub -> NFKB2p100_NFKB2p100_Ub
NFKB2p100_NFKB2p100cytoplasm -> NFKB2p100_NFKB2p100_Ub
ISGF3nucleus -> CXCL10gene
IRF3_IRF3nucleus -> CXCL10gene
CBP -> CXCL10gene
IRF3_IRF7nucleus -> CXCL10gene
External_Activator -> RELB
Mitochondrial_Activator -> ENDOGmitochondria
FADD -> TNF_TNFRSF1A_FADD_TRADD
TRADD -> TNF_TNFRSF1A_FADD_TRADD
TNF_TNFRSF1A -> TNF_TNFRSF1A_FADD_TRADD
PARP -> IPARP
CASP7nucleus -> IPARP
CASP3nucleus -> IPARP
External_Activator -> EP300
External_Activator -> IL1R1
External_Activator -> BCL3
External_Activator -> TLR2
External_Activator -> RIPK3
TRAF6 -> ILIB_IL1R1_MYD88_IRAK1_IRAK4_TRAF6
ILIB_IL1R1_MYD88_IRAK1_IRAK4 -> ILIB_IL1R1_MYD88_IRAK1_IRAK4_TRAF6
IRF5 -> IRF5_IRF5cytoplasm
RELAp65_NFBK1p50nucleus -> FASgene
External_Activator -> IRAK1
IRF1_IRF1nucleus -> IRF8
IRF2 -> IRF8
IRF5 -| TLR7_MYD88_TRAF6_IRF5
TRAF6 -> TLR7_MYD88_TRAF6_IRF5
TLR7_TLR7 -> TLR7_MYD88_TRAF6_IRF5
MYD88 -> TLR7_MYD88_TRAF6_IRF5
Bacteria -> LPS
Cell_Shrinkage -> Apoptosis
DNA_Fragmentation -> Apoptosis
Inactive_DNA_Repair -> Apoptosis
Inactivation_of_Protein_Synthesis -> Apoptosis
External_Activator -> DFFA
STAT1_STAT1_IRF9cytoplasm -> STAT1_STAT1_IRF9nucleus
ISGF3nucleus -> IFNAgene
IRF1_IRF1nucleus -> IFNAgene
IRF3_IRF3nucleus -> IFNAgene
IRF5_IRF5nucleus -> IFNAgene
IRF3_IRF7nucleus -> IFNAgene
IRF7_IRF7nucleus -> IFNAgene
STAT1_STAT1_IRF9nucleus -> IFNAgene
IRF3_IRF5nucleus -> IFNAgene
IRF2 -|? IFNAgene
Mitochondrial_Activator -> CYCSmytochondria
Mitochondrial_Activator -> BCL2
External_Activator -> MYD88
IRF8 -> OAS1gene
ISGF3nucleus -> OAS1gene
IRF1_IRF1nucleus -> OAS1gene
IRF5_IRF5nucleus -> OAS1gene
IRF7 -> IRF7_IRF7cytoplasm
STAT1_STAT1cytoplasm -> STAT1_STAT1nucleus_p1
External_Activator -> ProCASP2
CASP3cytoplasm -> CASP3nucleus
ISGF3nucleus -> EIF2AK2gene
IRF1_IRF1nucleus -> EIF2AK2gene
IFNGR -> STAT1
External_Activator -> CD40
IRF5 -> IRF5_IRF7cytoplasm
CASP6nucleus -> cLMNA
LMNA -> cLMNA
TLR3_TICAM1_TICAM2 -> TLR3_TICAM1_TICAM2_RIPK1
RIPK1 -> TLR3_TICAM1_TICAM2_RIPK1
EIF2AK2gene -> EIF2S1
DNA -> Fragmented_DNAnucleus
PDCD8nucleus -> Fragmented_DNAnucleus
ENDOGnucleus -> Fragmented_DNAnucleus
External_Activator -> IRF4
IRF1_IRF1nucleus -> HIST2H4gene
IRF2 -> HIST2H4gene
EP300 -> CBP
CREBBP -> CBP
BAK1 -> DIABLOcytoplasm
tBID -> DIABLOcytoplasm
DIABLOmitochondria -> DIABLOcytoplasm
BAX -> DIABLOcytoplasm
IRF5_IRF5nucleus -> BAK1gene
PTP -|? STAT1_STAT1nucleus_p2
STAT1_STAT1nucleus_p1 -> STAT1_STAT1nucleus_p2
TLR9_MYD88_TRAF6_IRF5 -> IRF5
Virus -> IRF5
TLR7_MYD88_TRAF6_IRF5 -> IRF5
IRAK4 -> TLR2_TLR6_TOLLIP_MYD88_IRAK1_IRAK4
TLR2_TLR6 -> TLR2_TLR6_TOLLIP_MYD88_IRAK1_IRAK4
TOLLIP -> TLR2_TLR6_TOLLIP_MYD88_IRAK1_IRAK4
IRAK1 -> TLR2_TLR6_TOLLIP_MYD88_IRAK1_IRAK4
MYD88 -> TLR2_TLR6_TOLLIP_MYD88_IRAK1_IRAK4
External_Activator -> Ub
ISGF3cytoplasm -> ISGF3nucleus
External_Activator -> IRAK2
IRF5_IRF5nucleus -> PLSCR1gene
IRF5_IRF5nucleus -> CXCL11gene
IRF7 -> IRF3_IRF7cytoplasm
IRF3 -> IRF3_IRF7cytoplasm
IRF1_IRF1nucleus -> STAT1gene
Fragmented_DNAnucleus -> DNA_Fragmentation
IDFFA -> DNA_Fragmentation
Ub -> NFKB2p100_RELB_Ub
NFKB2p100_RELBcytoplasm -> NFKB2p100_RELB_Ub
External_Activator -> TNFRSF1A
dsRNA -> EIF2AK2cytoplasm
External_Activator -> TLR6
IRF3 -> IRF3_IRF3cytoplasm
IRF8 -> G1P2gene
IRF1_IRF1nucleus -> G1P2gene
ISGF3nucleus -> G1P2gene
IRF3_IRF3nucleus -> G1P2gene
CBP -> G1P2gene
IRF3_IRF7nucleus -> G1P2gene
IRF4 -> G1P2gene
SPI1 -> G1P2gene
IRF2 -> G1P2gene
External_Activator -> TNFRSF10A
External_Activator -> IFNAR2
TRAF6 -> TLR5_MYD88_IRAK1_IRAK4_TRAF6
TLR5_MYD88_IRAK1_IRAK4 -> TLR5_MYD88_IRAK1_IRAK4_TRAF6
EIF2AK2_PRKRA -> TP53cytoplasm
External_Activator -> Proteasome
Bacteria -> Flagellin
External_Activator -> IKBKE
External_Activator -> ProCASP10
STAT1_STAT2 -> ISGF3cytoplasm
IRF9 -> ISGF3cytoplasm
NFKB2p52_NFKB2p52cytoplasm -> NFKB2p52_NFKB2p52nucleus
ProCASP1 -> CASP1
CASP4 -> CASP1
RELAp65_NFBK1p50nucleus -> BIRC3gene
Mitochondrial_Activator -> HTRA2mitochondria
CASP6_Activator -> CASP9
External_Activator -> TNFRSF10B
External_Activator -> PRKRA
DFFA -> IDFFA
CASP3nucleus -> IDFFA
RELA_NFKB1_Activator -> RELA_p65
External_Activator -> TNFRSF1B
ProCASP7 -> CASP7cytoplasm
Apoptosome -> CASP7cytoplasm
CASP10 -> CASP7cytoplasm
BIRC4cytoplasm -|? CASP7cytoplasm
CASP8 -> CASP7cytoplasm
CD40_CD40LG -> CD40_CD40LG_TRAF3
TRAF3 -> CD40_CD40LG_TRAF3
External_Activator -> HSPA1A
RELAp65_NFBK1p50nucleus -> BIRC4gene
External_Activator -> TLR7
External_Activator -> PRKCZ
IRF3_IRF5cytoplasm -> IRF3_IRF5nucleus
DAXX -> FASLG_FAS_FADD_FAF1_DAXX
FADD -> FASLG_FAS_FADD_FAF1_DAXX
FASLG_FAS -> FASLG_FAS_FADD_FAF1_DAXX
FAF1 -> FASLG_FAS_FADD_FAF1_DAXX
TNFSF13B -> TNFSF13B_TNFRSF17
TNFRSF17 -> TNFSF13B_TNFRSF17
IRF5_IRF5nucleus -> PMAIPgene
ISGF3nucleus -> IFIT2gene
IRF3_IRF3nucleus -> IFIT2gene
CBP -> IFIT2gene
IRF3_IRF7nucleus -> IFIT2gene
FAS -> FASLG_FAS
FASLG -> FASLG_FAS
IRF5_IRF7cytoplasm -> IRF5_IRF7nucleus
Proteasome -> NFKB2p52_NFKB2p52cytoplasm
NFKB2p100_NFKB2p100_Ub -> NFKB2p52_NFKB2p52cytoplasm
CHUK -> TNF_IKBKG_Complex
TNF_TNFRSF1A_FADD_TRADD_TRAF2_RIPK1 -> TNF_IKBKG_Complex
IKBKB -> TNF_IKBKG_Complex
IKBKG -> TNF_IKBKG_Complex
Mitochondrial_Activator -> DIABLOmitochondria
BCL2 -> BCL2_BAX
BAX -> BCL2_BAX
LPS -> TLR4
External_Activator -> TICAM2
TRAF2cytoplasm -> TNF_TNFRSF1B_TRAF2
TNF_TNFRSF1B -> TNF_TNFRSF1B_TRAF2
RELAp65_NFBK1p50nucleus -> TRAF2gene
External_Activator -> PTPN2
External_Activator -> CHUK
TP53cytoplasm -> TP53nucleus
Ub -|? NFKBIA
NFKBIA_RELAp65_NFKB1p50 -> NFKBIA
RELA_NFKB1_Activator -> NFKBIA
PDCD8mitochondria -> PDCD8cytoplasm
tBID -> PDCD8cytoplasm
IKBKG_CHUK_IKBKB -> NFKB2p100_NFKB2p100cytoplasm
NFKB2p100 -> NFKB2p100_NFKB2p100cytoplasm
IRF5 -| TLR9_MYD88_TRAF6_IRF5
TLR9_TLR9 -> TLR9_MYD88_TRAF6_IRF5
TRAF6 -> TLR9_MYD88_TRAF6_IRF5
MYD88 -> TLR9_MYD88_TRAF6_IRF5
IRF8 -> CYBBgene
SPI1 -> CYBBgene
IRF1cytoplasm -> IRF1_IRF1cytoplasm
IRF1_IRF1nucleus -> CCL5gene
tBID -> HTRA2cytoplasm
HTRA2mitochondria -> HTRA2cytoplasm
RELA_NFKB1_Activator -> NFKB1_p50
Triacyl_Lipopeptides -> TLR1_TLR2
IRF1_IRF1nucleus -> CIITAgene
IRF2 -> CIITAgene
TRAF6 -> TLR9_MYD88_IRAK1_IRAK4_TRAF6
TLR9_MYD88_IRAK1_IRAK4 -> TLR9_MYD88_IRAK1_IRAK4_TRAF6
Bacteria -> Viral_Bacterial_CpG
Virus -> Viral_Bacterial_CpG
EIF2AK2cytoplasm -> EIF2AK2_PRKRA
PRKRA -> EIF2AK2_PRKRA
External_Activator -> BID
RELAp65_NFBK1p50nucleus -> TRAF1gene
ISGF3nucleus -> IFNB1gene
IRF1_IRF1nucleus -> IFNB1gene
IRF3_IRF3nucleus -> IFNB1gene
IRF5_IRF5nucleus -> IFNB1gene
CBP -> IFNB1gene
IRF3_IRF7nucleus -> IFNB1gene
ATF2 -> IFNB1gene
STAT1_STAT1nucleus_p2 -> IFNB1gene
RELAp65_NFBK1p50nucleus -> IFNB1gene
IRF2 -|? IFNB1gene
TNFRSF10B -> TNFSF10_TNFSF10B
TNFSF10 -> TNFSF10_TNFSF10B
JAK1 -> IFNAR
TYK2 -> IFNAR
IFNAR2 -> IFNAR
IFNB1 -> IFNAR
IFNAR1 -> IFNAR
IFNA -> IFNAR
STAT1_STAT1nucleus_p2 -> ICAM1gene
External_Activator -> TRAF3
STAT1_STAT1nucleus_p2 -> CXCL9gene
DIABLOcytoplasm -| BIRC4cytoplasm
HTRA2cytoplasm -| BIRC4cytoplasm
tBID -> ENDOGcytoplasm
ENDOGmitochondria -> ENDOGcytoplasm
IRF8 -> HLA_Bgene
IRF2 -|? HLA_Bgene
Mitochondrial_Activator -> BCL2L1mitochondria
Bacteria -> Diacyl_Lipopeptides
CYCSmytochondria -> CYCScytoplasm
BAK1 -> CYCScytoplasm
tBID -> CYCScytoplasm
BAX -> CYCScytoplasm
ProCASP4 -> CASP4
External_Activator -> SPI1
Mitochondrial_Activator -> BAX
External_Activator -> RPS6KA5
TLR3_TICAM1_TICAM2_RIPK1 -> TLR3_TICAM1_TICAM2_RIPK1_RIPK3
RIPK3 -> TLR3_TICAM1_TICAM2_RIPK1_RIPK3
dsRNA -> TLR3_TLR3
TLR3 -> TLR3_TLR3
IRF5_IRF5nucleus -> SP100gene
TICAM1 -> TLR4_TICAM1_TICAM2
TICAM2 -> TLR4_TICAM1_TICAM2
TLR4 -> TLR4_TICAM1_TICAM2
CASP7cytoplasm -> CASP7nucleus
IRF1_IRF1_Activator -> CKII
ILIB_IL1R1 -> ILIB_IL1R1_MYD88_IRAK1_IRAK4
IRAK4 -> ILIB_IL1R1_MYD88_IRAK1_IRAK4
IRAK1 -> ILIB_IL1R1_MYD88_IRAK1_IRAK4
MYD88 -> ILIB_IL1R1_MYD88_IRAK1_IRAK4
External_Activator -> TIRAP
External_Activator -> SOCS1
CASP9 -> CASP6cytoplasm
ProCASP6 -> CASP6cytoplasm
PDCD8cytoplasm -> PDCD8nucleus
BID -> tBID
CASP8 -> tBID
CASP2 -> tBID
External_Activator -> GAS2
IRF1_IRF1nucleus -> PSMB9gene
IRF2 -> PSMB9gene
CHUK -> RELAp65_NFKB1p50cytoplasm
MAP3K7 -> RELAp65_NFKB1p50cytoplasm
IKBKB -> RELAp65_NFKB1p50cytoplasm
NFKBIA_RELAp65_NFKB1p50 -> RELAp65_NFKB1p50cytoplasm
PRKCZ -> RELAp65_NFKB1p50cytoplasm
RPS6KA5 -> RELAp65_NFKB1p50cytoplasm
TBK1 -> RELAp65_NFKB1p50cytoplasm
External_Activator -> PRKCD
BCL3 -> BCL3_NFKB2p52_NFKB2p52
NFKB2p52_NFKB2p52nucleus -> BCL3_NFKB2p52_NFKB2p52
IRF1_IRF1nucleus -> TNFSF10gene
IRF5_IRF5nucleus -> TNFSF10gene
TP53nucleus -> TNFRSF10Bgene
TNF_BAG4_TNFRSF1A -> BAG4
External_Activator -> BAG4
IRAK4 -> TLR5_MYD88_IRAK1_IRAK4
TLR5_TLR5 -> TLR5_MYD88_IRAK1_IRAK4
IRAK1 -> TLR5_MYD88_IRAK1_IRAK4
MYD88 -> TLR5_MYD88_IRAK1_IRAK4
External_Activator -> TLR9
TLR3_TICAM1_TICAM2 -> TLR3_TICAM1_TICAM2_TRAF6
TRAF6 -> TLR3_TICAM1_TICAM2_TRAF6
PKC -> IRF1cytoplasm
CKII -> IRF1cytoplasm
PKA -> IRF1cytoplasm
CASP3_Activator -> ProCASP3
IRF8 -> G1P3gene
IRF9 -> STAT1_STAT1_IRF9cytoplasm
STAT1 -> STAT1_STAT1_IRF9cytoplasm
RELB -> NFKB2p100_RELBcytoplasm
CHUK_CHUK -> NFKB2p100_RELBcytoplasm
NFKB2p100 -> NFKB2p100_RELBcytoplasm
HSPA1A -> PDCD8_HSPA1A
PDCD8cytoplasm -> PDCD8_HSPA1A
APAF1_CYCS -> Apoptosome
CASP9 -> Apoptosome
External_Activator -> MAP3K7
CYCScytoplasm -> APAF1_CYCS
APAF1 -> APAF1_CYCS
CASP7_Activator -> ProCASP7
External_Activator -> RIPK1
External_Activator -> TYK2
External_Activator -> TLR3
Mitochondrial_Activator -> PDCD8mitochondria
External_Activator -> IKBKG
TNF_TNFRSF1A_FADD_TRADD -> CASP10
ProCASP10 -> CASP10
IRF5 -> IRF3_IRF5cytoplasm
TRAF6 -> TLR2_TLR6_TOLLIP_MYD88_IRAK1_IRAK4_TRAF6
TLR2_TLR6_TOLLIP_MYD88_IRAK1_IRAK4 -> TLR2_TLR6_TOLLIP_MYD88_IRAK1_IRAK4_TRAF6
External_Activator -> TNFRSF17
IRF1_IRF1nucleus -> IRF2gene
TLR9_TLR9 -> TLR9_MYD88_IRAK1_IRAK4
IRAK4 -> TLR9_MYD88_IRAK1_IRAK4
IRAK1 -> TLR9_MYD88_IRAK1_IRAK4
MYD88 -> TLR9_MYD88_IRAK1_IRAK4
IRF1_IRF1nucleus -> GBP1gene
IRF2 -> GBP1gene
IRF1_IRF1_Activator -> PKA
IRF5_IRF5nucleus -> RIPK1gene
IKBKE_TBK1 -> IRF3
TLR3_TICAM1_TICAM2_TBK1 -> IRF3
DNA_Fragmentation -> Fragmented_DNAcytoplasm
IL1R1 -> ILIB_IL1R1
ILIB -> ILIB_IL1R1
TP53nucleus -> FASLGgene
IRF1_IRF1nucleus -> FASLGgene
TP53nucleus -> MDM2gene
IRF5_IRF5nucleus -> PRKRAgene
$APAF1: External_Activator
$APAF1_CYCS: (APAF1 & CYCScytoplasm)
$APAF1gene: TP53nucleus
$ATF2: External_Activator
$Apoptosis: (((DNA_Fragmentation | Inactive_DNA_Repair) | Cell_Shrinkage) | Inactivation_of_Protein_Synthesis)
$Apoptosome: (APAF1_CYCS & CASP9)
$BAD: Mitochondrial_Activator
$BAG4: (External_Activator | TNF_BAG4_TNFRSF1A)
$BAG4_TNFRSF1A: (BAG4 & TNFRSF1A)
$BAK1: Mitochondrial_Activator
$BAK1gene: IRF5_IRF5nucleus
$BAX: Mitochondrial_Activator
$BBC3gene: TP53nucleus
$BCL2: Mitochondrial_Activator
$BCL2A1: RELAp65_NFBK1p50nucleus
$BCL2A1gene: RELAp65_NFBK1p50nucleus
$BCL2L1_BAD: (BCL2L1mitochondria & BAD)
$BCL2L1gene: RELAp65_NFBK1p50nucleus
$BCL2L1mitochondria: Mitochondrial_Activator
$BCL2_BAX: (BCL2 & BAX)
$BCL3: External_Activator
$BCL3_NFKB2p52_NFKB2p52: (BCL3 & NFKB2p52_NFKB2p52nucleus)
$BID: External_Activator
$BIRC2: External_Activator
$BIRC3gene: RELAp65_NFBK1p50nucleus
$BIRC4cytoplasm: !(DIABLOcytoplasm | HTRA2cytoplasm)
$BIRC4gene: RELAp65_NFBK1p50nucleus
$CASP1: (ProCASP1 & CASP4)
$CASP10: (ProCASP10 & TNF_TNFRSF1A_FADD_TRADD)
$CASP2: (ProCASP2 & Fragmented_DNAcytoplasm)
$CASP3cytoplasm: (ProCASP3 & ((Apoptosome | CASP4) | CASP8))
$CASP3gene: (CASP3cytoplasm | IRF5_IRF5nucleus)
$CASP3nucleus: CASP3cytoplasm
$CASP4: ProCASP4
$CASP6cytoplasm: (ProCASP6 & CASP9)
$CASP6nucleus: CASP6cytoplasm
$CASP7cytoplasm: (ProCASP7 & ((Apoptosome | CASP10) | CASP8))
$CASP7nucleus: CASP7cytoplasm
$CASP8: (ProCASP8 & (((FASLG_FAS_FADD_FAF1_DAXX | TNFSF10_TNFSF10B_FADD) | TNFSF10_TNFRSF10A_FADD) | FASLG_FAS_FADD_FAF1_DAXX_CFLAR))
$CASP9: CASP6_Activator
$CBP: (EP300 & CREBBP)
$CCL5gene: IRF1_IRF1nucleus
$CD40: External_Activator
$CD40_CD40LG: (CD40 & CD40LG)
$CD40_CD40LG_TRAF3: (CD40_CD40LG & TRAF3)
$CFLAR: External_Activator
$CFLARgene: RELAp65_NFBK1p50nucleus
$CHUK: External_Activator
$CHUK_CHUK: (CHUK & MAP3K14)
$CIITAgene: (IRF2 | IRF1_IRF1nucleus)
$CKII: IRF1_IRF1_Activator
$CREBBP: External_Activator
$CXCL10gene: ((CBP & (IRF3_IRF3nucleus | IRF3_IRF7nucleus)) | ISGF3nucleus)
$CXCL11gene: IRF5_IRF5nucleus
$CXCL9gene: STAT1_STAT1nucleus_p2
$CYBBgene: (IRF8 & SPI1)
$CYCScytoplasm: (CYCSmytochondria & ((BAK1 | tBID) | BAX))
$CYCSmytochondria: Mitochondrial_Activator
$Cell_Shrinkage: (cLMNA | cGAS2)
$DAXX: External_Activator
$DFFA: External_Activator
$DIABLOcytoplasm: (DIABLOmitochondria & ((BAK1 | tBID) | BAX))
$DIABLOmitochondria: Mitochondrial_Activator
$DNA: External_Activator
$DNA_Fragmentation: (Fragmented_DNAnucleus | IDFFA)
$Diacyl_Lipopeptides: Bacteria
$EIF2AK2_PRKRA: (EIF2AK2cytoplasm & PRKRA)
$EIF2AK2cytoplasm: dsRNA
$EIF2AK2gene: (IRF1_IRF1nucleus | ISGF3nucleus)
$EIF2S1: EIF2AK2gene
$ENDOGcytoplasm: (tBID & ENDOGmitochondria)
$ENDOGmitochondria: Mitochondrial_Activator
$ENDOGnucleus: ENDOGcytoplasm
$EP300: External_Activator
$FADD: External_Activator
$FAF1: External_Activator
$FAS: External_Activator
$FASLG_FAS: (FASLG & FAS)
$FASLG_FAS_FADD_FAF1_DAXX: (FASLG_FAS & ((DAXX & FADD) & FAF1))
$FASLG_FAS_FADD_FAF1_DAXX_CFLAR: (FASLG_FAS_FADD_FAF1_DAXX & CFLAR)
$FASLGgene: (TP53nucleus | IRF1_IRF1nucleus)
$FASgene: RELAp65_NFBK1p50nucleus
$Flagellin: Bacteria
$Fragmented_DNAcytoplasm: DNA_Fragmentation
$Fragmented_DNAnucleus: (DNA & (PDCD8nucleus | ENDOGnucleus))
$G1P2gene: ((((IRF1_IRF1nucleus & ((IRF8 & IRF4) & SPI1)) | (IRF2 & ((IRF8 & IRF4) & SPI1))) | ISGF3nucleus) | (CBP & (IRF3_IRF3nucleus | IRF3_IRF7nucleus)))
$G1P3gene: IRF8
$GAS2: External_Activator
$GBP1gene: (IRF1_IRF1nucleus | IRF2)
$HIST2H4gene: (IRF2 | IRF1_IRF1nucleus)
$HLA_Bgene: IRF8
$HSPA1A: External_Activator
$HTRA2cytoplasm: (tBID & HTRA2mitochondria)
$HTRA2mitochondria: Mitochondrial_Activator
$ICAM1gene: STAT1_STAT1nucleus_p2
$IDFFA: (DFFA & CASP3nucleus)
$IER3gene: RELAp65_NFBK1p50nucleus
$IFIT1gene: IRF5_IRF5nucleus
$IFIT2gene: (ISGF3nucleus | (CBP & (IRF3_IRF3nucleus | IRF3_IRF7nucleus)))
$IFNAR: ((IFNB1 & (((JAK1 & TYK2) & IFNAR2) & IFNAR1)) | (IFNA & (((JAK1 & TYK2) & IFNAR2) & IFNAR1)))
$IFNAR1: External_Activator
$IFNAR2: External_Activator
$IFNA_IFNA: IFNA
$IFNAgene: (((((((IRF3_IRF5nucleus | IRF3_IRF7nucleus) | IRF5_IRF5nucleus) | ISGF3nucleus) | IRF1_IRF1nucleus) | STAT1_STAT1_IRF9nucleus) | IRF7_IRF7nucleus) | IRF3_IRF3nucleus)
$IFNB1_IFNB1: IFNB1
$IFNB1gene: (((((ISGF3nucleus | IRF3_IRF3nucleus) | IRF5_IRF5nucleus) | STAT1_STAT1nucleus_p2) | (RELAp65_NFBK1p50nucleus & (((IRF3_IRF3nucleus & CBP) & IRF3_IRF7nucleus) & ATF2))) | IRF1_IRF1nucleus)
$IFNGR: (IFNG & ((IFNGR1 & JAK2) & IFNGR2))
$IFNGR1: External_Activator
$IFNGR2: External_Activator
$IFR5gene: (TP53nucleus | STAT1_STAT1_IRF9nucleus)
$IKBKB: External_Activator
$IKBKE: External_Activator
$IKBKE_TBK1: (TLR4_TICAM1_TICAM2 & (IKBKE & TBK1))
$IKBKG: External_Activator
$IKBKG_CHUK_IKBKB: ((IKBKG & ((CHUK & IKBKB) & MAP3K7IP1_MAP3K7IP2_MAP3K7)) | (TLR3_TICAM1_TICAM2_RIPK1_RIPK3 & ((CHUK & IKBKB) & IKBKG)))
$IL12Bgene: IRF1_IRF1nucleus
$IL15gene: IRF1_IRF1nucleus
$IL1Bgene: (IRF8 & SPI1)
$IL1R1: External_Activator
$ILIB_IL1R1: (ILIB & IL1R1)
$ILIB_IL1R1_MYD88_IRAK1_IRAK4: (ILIB_IL1R1 & ((IRAK4 & IRAK1) & MYD88))
$ILIB_IL1R1_MYD88_IRAK1_IRAK4_TRAF6: (ILIB_IL1R1_MYD88_IRAK1_IRAK4 & TRAF6)
$IPARP: (PARP & (CASP7nucleus | CASP3nucleus))
$IRAK1: External_Activator
$IRAK2: External_Activator
$IRAK4: External_Activator
$IRF1_IRF1cytoplasm: IRF1cytoplasm
$IRF1_IRF1nucleus: IRF1_IRF1cytoplasm
$IRF1cytoplasm: ((PKA | PKC) | CKII)
$IRF1gene: STAT1_STAT1nucleus_p2
$IRF2: IRF2_Activator
$IRF2gene: IRF1_IRF1nucleus
$IRF3: (IKBKE_TBK1 | TLR3_TICAM1_TICAM2_TBK1)
$IRF3_IRF3cytoplasm: IRF3
$IRF3_IRF3nucleus: IRF3_IRF3cytoplasm
$IRF3_IRF5cytoplasm: IRF5
$IRF3_IRF5nucleus: IRF3_IRF5cytoplasm
$IRF3_IRF7cytoplasm: (IRF3 & IRF7)
$IRF3_IRF7nucleus: IRF3_IRF7cytoplasm
$IRF4: External_Activator
$IRF5: ((TLR7_MYD88_TRAF6_IRF5 | Virus) | TLR9_MYD88_TRAF6_IRF5)
$IRF5_IRF5cytoplasm: IRF5
$IRF5_IRF5nucleus: IRF5_IRF5cytoplasm
$IRF5_IRF7cytoplasm: IRF5
$IRF5_IRF7nucleus: IRF5_IRF7cytoplasm
$IRF7: IKBKE_TBK1
$IRF7_IRF7cytoplasm: IRF7
$IRF7_IRF7nucleus: IRF7_IRF7cytoplasm
$IRF8: (IRF1_IRF1nucleus | IRF2)
$IRF9: External_Activator
$ISGF3cytoplasm: (STAT1_STAT2 & IRF9)
$ISGF3nucleus: ISGF3cytoplasm
$Inactivation_of_Protein_Synthesis: EIF2S1
$Inactive_DNA_Repair: IPARP
$JAK1: External_Activator
$JAK2: External_Activator
$LMNA: External_Activator
$LPS: Bacteria
$MAP3K14: ((CD40_CD40LG_TRAF3 | TNF_TNFRSF1B_TRAF2) | TNFSF13B_TNFRSF17_TRAF5)
$MAP3K7: External_Activator
$MAP3K7IP1: External_Activator
$MAP3K7IP1_MAP3K7IP2_MAP3K7: (((((((TLR7_MYD88_IRAK1_IRAK4_TRAF6 & ((MAP3K7 & MAP3K7IP2) & MAP3K7IP1)) | (TLR1_TLR2_TIRAP_MYD88_IRAK2_IRAK1_IRAK4_TRAF6 & ((MAP3K7 & MAP3K7IP2) & MAP3K7IP1))) | (ILIB_IL1R1_MYD88_IRAK1_IRAK4_TRAF6 & ((MAP3K7 & MAP3K7IP2) & MAP3K7IP1))) | (TLR9_MYD88_IRAK1_IRAK4_TRAF6 & ((MAP3K7 & MAP3K7IP2) & MAP3K7IP1))) | (TLR5_MYD88_IRAK1_IRAK4_TRAF6 & ((MAP3K7 & MAP3K7IP2) & MAP3K7IP1))) | (TLR2_TLR6_TOLLIP_MYD88_IRAK1_IRAK4_TRAF6 & ((MAP3K7 & MAP3K7IP2) & MAP3K7IP1))) | (TLR3_TICAM1_TICAM2_TRAF6 & ((MAP3K7 & MAP3K7IP2) & MAP3K7IP1)))
$MAP3K7IP2: External_Activator
$MDM2gene: TP53nucleus
$MYD88: External_Activator
$NFKB1_p50: RELA_NFKB1_Activator
$NFKB2p100: External_Activator
$NFKB2p100_NFKB2p100_Ub: (NFKB2p100_NFKB2p100cytoplasm & Ub)
$NFKB2p100_NFKB2p100cytoplasm: (NFKB2p100 & IKBKG_CHUK_IKBKB)
$NFKB2p100_RELB_Ub: (NFKB2p100_RELBcytoplasm & Ub)
$NFKB2p100_RELBcytoplasm: (NFKB2p100 & (RELB & CHUK_CHUK))
$NFKB2p52_NFKB2p52cytoplasm: (NFKB2p100_NFKB2p100_Ub & Proteasome)
$NFKB2p52_NFKB2p52nucleus: NFKB2p52_NFKB2p52cytoplasm
$NFKB2p52_RELBcytoplasm: (NFKB2p100_RELB_Ub & Proteasome)
$NFKB2p52_RELBnucleus: NFKB2p52_RELBcytoplasm
$NFKBIA: (RELA_NFKB1_Activator | NFKBIA_RELAp65_NFKB1p50)
$NFKBIA_RELAp65_NFKB1p50: ((TNF_IKBKG_Complex & ((RELA_p65 & NFKBIA) & NFKB1_p50)) | (IKBKG_CHUK_IKBKB & ((RELA_p65 & NFKBIA) & NFKB1_p50)))
$NOS2Agene: External_Activator
$OAS1gene: (((IRF5_IRF5nucleus | IRF8) | ISGF3nucleus) | IRF1_IRF1nucleus)
$PARP: External_Activator
$PDCD8_HSPA1A: (PDCD8cytoplasm & HSPA1A)
$PDCD8cytoplasm: (tBID & PDCD8mitochondria)
$PDCD8mitochondria: Mitochondrial_Activator
$PDCD8nucleus: PDCD8cytoplasm
$PKA: IRF1_IRF1_Activator
$PKC: IRF1_IRF1_Activator
$PLSCR1gene: IRF5_IRF5nucleus
$PMAIPgene: IRF5_IRF5nucleus
$PRKCD: External_Activator
$PRKCZ: External_Activator
$PRKRA: External_Activator
$PRKRAgene: IRF5_IRF5nucleus
$PSMB9gene: (IRF1_IRF1nucleus | IRF2)
$PTP: External_Activator
$PTPN2: External_Activator
$ProCASP1: External_Activator
$ProCASP10: External_Activator
$ProCASP2: External_Activator
$ProCASP3: CASP3_Activator
$ProCASP4: External_Activator
$ProCASP6: CASP6_Activator
$ProCASP7: CASP7_Activator
$ProCASP8: External_Activator
$Proteasome: External_Activator
$RELA_p65: RELA_NFKB1_Activator
$RELAp65_NFBK1p50nucleus: RELAp65_NFKB1p50cytoplasm
$RELAp65_NFKB1p50cytoplasm: (NFKBIA_RELAp65_NFKB1p50 & (((((CHUK | MAP3K7) | IKBKB) | PRKCZ) | RPS6KA5) | TBK1))
$RELB: External_Activator
$RIPK1: External_Activator
$RIPK1gene: IRF5_IRF5nucleus
$RIPK3: External_Activator
$RPS6KA5: External_Activator
$SOCS1: External_Activator
$SOCS3: External_Activator
$SOD2gene: RELAp65_NFBK1p50nucleus
$SP100gene: IRF5_IRF5nucleus
$SPI1: External_Activator
$STAT1: IFNGR
$STAT1_STAT1_IRF9cytoplasm: (STAT1 & IRF9)
$STAT1_STAT1_IRF9nucleus: STAT1_STAT1_IRF9cytoplasm
$STAT1_STAT1cytoplasm: (STAT1 & PRKCD)
$STAT1_STAT1nucleus_p1: STAT1_STAT1cytoplasm
$STAT1_STAT1nucleus_p2: STAT1_STAT1nucleus_p1
$STAT1_STAT2: (STAT1 & STAT2)
$STAT1gene: IRF1_IRF1nucleus
$STAT2: IFNAR
$TAP1gene: (IRF1_IRF1nucleus | IRF2)
$TBK1: External_Activator
$TICAM1: External_Activator
$TICAM2: External_Activator
$TIRAP: External_Activator
$TLR1_TLR2: Triacyl_Lipopeptides
$TLR1_TLR2_TIRAP_MYD88_IRAK2_IRAK1_IRAK4: (TLR1_TLR2 & ((((IRAK2 & IRAK4) & IRAK1) & MYD88) & TIRAP))
$TLR1_TLR2_TIRAP_MYD88_IRAK2_IRAK1_IRAK4_TRAF6: (TLR1_TLR2_TIRAP_MYD88_IRAK2_IRAK1_IRAK4 & TRAF6)
$TLR2: External_Activator
$TLR2_TLR6: (TLR2 & (Diacyl_Lipopeptides & TLR6))
$TLR2_TLR6_TOLLIP_MYD88_IRAK1_IRAK4: (TLR2_TLR6 & (((IRAK4 & TOLLIP) & IRAK1) & MYD88))
$TLR2_TLR6_TOLLIP_MYD88_IRAK1_IRAK4_TRAF6: (TLR2_TLR6_TOLLIP_MYD88_IRAK1_IRAK4 & TRAF6)
$TLR3: External_Activator
$TLR3_TICAM1_TICAM2: (TLR3_TLR3 & (TICAM1 & TICAM2))
$TLR3_TICAM1_TICAM2_RIPK1: (TLR3_TICAM1_TICAM2 & RIPK1)
$TLR3_TICAM1_TICAM2_RIPK1_RIPK3: (TLR3_TICAM1_TICAM2_RIPK1 & RIPK3)
$TLR3_TICAM1_TICAM2_TBK1: (TLR3_TICAM1_TICAM2 & TBK1)
$TLR3_TICAM1_TICAM2_TRAF6: (TLR3_TICAM1_TICAM2 & TRAF6)
$TLR3_TLR3: (dsRNA & TLR3)
$TLR4: LPS
$TLR4_TICAM1_TICAM2: (TLR4 & (TICAM1 & TICAM2))
$TLR5: External_Activator
$TLR5_MYD88_IRAK1_IRAK4: (TLR5_TLR5 & ((IRAK4 & IRAK1) & MYD88))
$TLR5_MYD88_IRAK1_IRAK4_TRAF6: (TLR5_MYD88_IRAK1_IRAK4 & TRAF6)
$TLR5_TLR5: (TLR5 & Flagellin)
$TLR6: External_Activator
$TLR7: External_Activator
$TLR7_MYD88_IRAK1_IRAK4: (TLR7_TLR7 & ((IRAK4 & IRAK1) & MYD88))
$TLR7_MYD88_IRAK1_IRAK4_TRAF6: (TLR7_MYD88_IRAK1_IRAK4 & TRAF6)
$TLR7_MYD88_TRAF6_IRF5: ((TLR7_TLR7 & (TRAF6 & MYD88)) & !IRF5)
$TLR7_TLR7: (TLR7 & ssRNA)
$TLR9: External_Activator
$TLR9_MYD88_IRAK1_IRAK4: (TLR9_TLR9 & ((IRAK4 & IRAK1) & MYD88))
$TLR9_MYD88_IRAK1_IRAK4_TRAF6: (TLR9_MYD88_IRAK1_IRAK4 & TRAF6)
$TLR9_MYD88_TRAF6: TLR9_MYD88_IRAK1_IRAK4_TRAF6
$TLR9_MYD88_TRAF6_IRF5: ((TLR9_TLR9 & (TRAF6 & MYD88)) & !IRF5)
$TLR9_TLR9: (TLR9 & Viral_Bacterial_CpG)
$TNFRSF10A: External_Activator
$TNFRSF10B: External_Activator
$TNFRSF10Bgene: TP53nucleus
$TNFRSF17: External_Activator
$TNFRSF1A: External_Activator
$TNFRSF1B: External_Activator
$TNFSF10_TNFRSF10A: (TNFSF10 & TNFRSF10A)
$TNFSF10_TNFRSF10A_FADD: (TNFSF10_TNFRSF10A & FADD)
$TNFSF10_TNFSF10B: (TNFSF10 & TNFRSF10B)
$TNFSF10_TNFSF10B_FADD: (TNFSF10_TNFSF10B & FADD)
$TNFSF10gene: (IRF1_IRF1nucleus | IRF5_IRF5nucleus)
$TNFSF13B_TNFRSF17: (TNFSF13B & TNFRSF17)
$TNFSF13B_TNFRSF17_TRAF5: (TNFSF13B_TNFRSF17 & TRAF5)
$TNF_BAG4_TNFRSF1A: (TNF & BAG4_TNFRSF1A)
$TNF_IKBKG_Complex: (TNF_TNFRSF1A_FADD_TRADD_TRAF2_RIPK1 & ((CHUK & IKBKB) & IKBKG))
$TNF_TNFRSF1A: TNF_BAG4_TNFRSF1A
$TNF_TNFRSF1A_FADD_TRADD: (TNF_TNFRSF1A & (FADD & TRADD))
$TNF_TNFRSF1A_FADD_TRADD_TRAF2_RIPK1: (TNF_TNFRSF1A_FADD_TRADD & (TRAF2cytoplasm & RIPK1))
$TNF_TNFRSF1B: (TNF & TNFRSF1B)
$TNF_TNFRSF1B_TRAF2: (TNF_TNFRSF1B & TRAF2cytoplasm)
$TOLLIP: External_Activator
$TP53cytoplasm: EIF2AK2_PRKRA
$TP53nucleus: TP53cytoplasm
$TRADD: External_Activator
$TRAF1gene: RELAp65_NFBK1p50nucleus
$TRAF2cytoplasm: External_Activator
$TRAF2gene: RELAp65_NFBK1p50nucleus
$TRAF3: External_Activator
$TRAF5: External_Activator
$TRAF6: External_Activator
$TYK2: External_Activator
$Triacyl_Lipopeptides: Bacteria
$Ub: External_Activator
$Viral_Bacterial_CpG: (Virus | Bacteria)
$cGAS2: (GAS2 & CASP3nucleus)
$cLMNA: (LMNA & CASP6nucleus)
$dsRNA: Virus
$ssRNA: Virus
$tBID: (BID & (CASP8 | CASP2))